Los ntawm tam sim no, peb txhua tus paub txog cov vitamins thiab minerals uas yuav tsum yog peb cov zaub mov noj - Vitamin C, calcium, magnesium, thiab lwm yam. Lawv tsis yog ua kom peb noj qab haus huv, lawv txhawb nqa peb. Yog vim li cas lawv thiaj hu ua "yam tseem ceeb." Tab sis muaj lwm chav kawm ntawm cov tebchaw hu ua "micronutrients" lossis "phytonutrients" uas muaj cov as-ham loj hauv kev pab peb kom noj qab haus huv.
Thiab tusTus apigeninPeb tab tom tham txog niaj hnub no yog ib txwm muaj tshwm sim ntawm cov nroj tsuag uas tiv thaiv lawv tus kheej thiab yog pathogens, thiab yog dav pom hauv cov nroj tsuag xws li chamomile, parsley, thiab celery, thiab celery. Tib neeg tau tsim kev sib raug zoo nrog kev sib raug zoo ntawm cov nroj tsuag - lawv cov khoom siv tshuaj tua kab mob thiab cov riam phom ntuj tiv thaiv kab mob thiab kev laus.
Dab tsi yuav Apigenin ua?
Kuv cellular-qib anti-o tuaj yeem tiv thaiv: los ntawm kev ywj pheej pub dawb rau kev txhawb nqa kev noj qab haus huv
Nyob rau ntawm qib cellular, apigenin tseem tshuav oxidating kev ntxhov siab los ntawm nruab nrab dawb radicals thiab inhibiting kev tawm ntawm cov pro-inflammatory secitures (piv txwv, tnf-, IL-6). Qhov no dual antioxidant thiab anti-inflatoryism kev teev hawm muab nws qhov tshwj xeeb kom zoo dua hauv kev sib cav, "roj pedal ntawm kev laus".
- Daim tawv nqaij Noj Qab Haus Huv:Cov kev tshawb fawb soj ntsuam tau ua pov thawj tias Apigenin ntawm 0.5% -2% kev tsim tawm rau sebum, thiab tam sim no tau koom nrog cov qauv kev laus ntawm qhov kawg los tiv thaiv kev laus cov khoom lag luam cov khoom lag luam nyuaj.
- Immunomodulation:Los ntawm kev tswj hwm qhov sib npaug ntawm TH17 / Treg cells, Apigenin tuaj yeem daws cov kab mob ntawm lub ntuj chim rau kev mob nkeeg xws li mob caj dab thiab ua xua.
- Kev tswj hwm qhov mob:Cov kev sim tsiaj qhia tias Apigenin (50 mg / kg / d) cuam tshuam txog kev ua kom muaj mob sib piv rau qhov ntawd ntawm qee cov tshuaj uas tsis yog sterio.
Ⅱmetabolic thiab endocrine noj qab haus huv: los ntawm kev ntxhov siab kom cov leeg loj hlob ua kom zoo
Cov kev ntxhov siab thiab cov teeb meem metabolic tau coj los ntawm kev ua neej nyob niaj hnub yog nyob rau hauv kev yuav tsum muaj kev tiv thaiv ntuj thiab kev cuam tshuam kev nyab xeeb. ApoGenin tau ua tiav ntau txoj kev txhawb nqa met-medensional los ntawm phiaj rau HPA axis thiab ampk txoj kev:
- Pw thiab kev ntxhov siab tswj: Inhibits cortisol overproduction thiab txhim kho kev ua si gaba receptor, conferring sasting chamomile-zoo li cov khoom siv tshuaj yej. Hauv kev sim tshuaj sim, kev sib tw txhua hnub ntawm 25mg Apigenin tau txo lub sijhawm pw tsaug zog.
- Cov tshuaj sib luag thiab cov leeg nqaij synthesis: Up-tswj hwm cov lus qhia ntawm CYP17A1, tus tseem ceeb enzyme hauv cov qib kev poob zoo, kom ncua kev poob ntawm androgen qib nrog hnub nyoog hauv cov txiv neej; Lub caij no, ua kom lub mtor txoj kev los txhawb cov kev loj hlob ntawm myo-satellite hlwb. Cov cuab yeej no ua rau nws nyiam cov khoom nyiam hauv kev ua si noj zaub mov noj.
Plawv thiab Lub Hlwb Noj Qab Haus Huv: Los ntawm Kev Tiv Thaiv Kab Mob rau Neuroinflamation Cov Kev Cai Tswj
Nyob rau hauv teb rau ob tug neeg tua neeg kev noj qab nyob zoo thiab cov kab mob plawv thiab cov kab mob neurodegenerative - Apigenin tau muaj kev tiv thaiv kev tiv thaiv zoo:
- Cardioprot:Cov kev tshawb fawb tsiaj hauv cov qauv ntshav qab zib tau qhia tias apigenin (20 mg / kg / d) kev txwv tsis pub muaj hnub nyoog hauv MyScardial ntawm cov hnub nyoog ntau lawm thiab NOx4-doliated oxidative kev puas tsuaj.
- Lub Hlwb Noj Qab Haus Huv:Txwv tsis pub muaj microglia los ntawm kev nkag mus rau cov ntshav-lub hlwb lub hlwb thiab txo cov plaque deposition thiab tau cov protein hyperphosphorhlepation. Hauv Alzheimer tus kab mob kab mob, tus neeg muaj nuj nqi ua haujlwm cov qhab nia ntawm pab pawg neeg siv nyiaj tau nce ntau dua 30%.
Ⅳ Tiv Thaiv Mob Cancer thiab Cellular autophagy: ib tug neeg tiv thaiv ntuj rau cov hom phiaj meej
Raws li ib tug autophagy inducer thiab oncogene inhibitor, Apigenin pom los tiv thaiv mob cancer los ntawm cov kev xav ntau:
- Xaiv CyTotoxicity:Hauv kev mob cancer mis (MCF-7), pc-3) thiab lwm yam kab mob hlwb (apigenin down-tswj hwm g2 / m theem thaiv kev thaiv nrog me me ntawm cov hlwb.
- Synergistic tshuaj lom neeg lub hwj chim:Ua ke nrog paclitaxel, nws tuaj yeem rov qab qog multidrug tsis kam thiab txo cov kev yuav tsum tau ua. Peb theem II cov kev tshawb fawb tshawb fawb tau ua los tshawb nrhiav nws cov kev siv hauv kev kho vaj tse.
Tag
Cov kev lag luam ntxiv tau khawm Apigenin vim tias nws them tau txhua yam muaj peev xwm kawm ua ntej. Cov koob tshuaj raug yog 50-400 mg ib hnub, thiab kuv pom zoo kom nws thaum hmo ntuj, raws li 100 mg lossis ntau dua tuaj yeem ua rau koj tsaug zog (uas yog vim li cas ntau tus neeg siv nws ua ib qho kev pw tsaug zog ntxiv). Hauv ntej, Apigenin yog ib qho classic "txhua yam zoo, tsis muaj phem" Micronutrient. Raws li kev tshawb fawb tau ua tiav ntau, peb yog kev ntseeg siab nws yuav pab txhawb ntau rau tib neeg kev noj qab haus huv.
Siv:
1. VENHI B, li al. (2019). Apigenin cov kev cuam tshuam anticancer.Phau Ntawv European ntawm Pharmacology
2. Lis r, li al. (2020). Neuroprotrotecial mab tawj.Phytomedicine
3. ClinicalTrials.gov ID: NCT04828525
4. Phau Ntawv European ntawm Pharmacology, 2019
5. Phau ntawv Journal ntawm NeuroinFrammation, 2020
6. Cns Neuroscience & Kho, 2018
7. J. agic. Zaub mov chem . 2021
8. Mol. Noj haus huv. Zaub mov res . 2020
